Cannabidiol and Fragile X syndrome

July 13th, 2023

A/Prof Dr Helen (Honey) Heussler MD, webinar recording 13 July 2023. (from FX Research Roundup webinar)

Dr Honey Heussler describes the scientific rationale underpinning the RECONNECT cannabidiol (CBD) FX clinical trial currently underway (2023 and 2024) in Adelaide, Brisbane, Melbourne & Sydney which is seeking to understand whether the (Zynerba) ZYGEL CBD transdermal gel product helps in some behavioural issues associated with Fragile X syndrome.

Dr Heussler outlined the working of the human endocannabinoid system, the impact of Fragile X syndrome on that system, and how cannabidiol (non-THC CBD) can provide regulation and control. Dr Heussler also outlined the operation and findings of the earlier clinical trial phases which have preceded Zynerba’s current RECONNECT study.

The RECONNECT study remains open in Australia until 31 March 2024. Individuals with a diagnosis of Fragile X syndrome and who are aged 3-22 years old and have behavioural symptoms may be eligible to participate in the study.

Dr Heussler is a Developmental and Behavioural Paediatrician with a dual qualification in Sleep Medicine. She is Medical Director of the Child Development Program at the Children’s Health Queensland Hospital and Health Service in Brisbane, and runs a Fragile X Clinic at the Queensland Children’s Hospital.

Watch the video recording of the webinar on our youtube channel:



Survey for parents / carers of adults with Fragile X syndrome

FRAGILE X | ADULTS & AGEING. We're undertaking the first Australian study on the support needs, health & wellbeing of ADULTS with Fragile X syndrome. Our goal is to enhance quality of life for adults with Fragile X syndrome as they age. We invite parents or carers to participate in our SURVEY. The survey has questions about: 1. GENERAL HEALTH AND WELLBEING of the adult with Fragile X syndrome. 2. EFFECTIVENESS OF EXISTING SUPPORTS for the adult with Fragile X syndrome as they age. 3. FUTURE PLANNING concerns of families & carers who provide support 4. ANY GAPS IN SUPPORTS OR SERVICES which may impede best outcomes in care. From the information contributed through the Survey we will develop training modules for frontline carers and tools for advocacy. The Survey can be completed ONLINE, in PAPER FORM, or by PHONE. Contact us for more information - or 1300 394 636

Fragile X Logo
Registered Charity Logo